I have a laundry room in the basement. It didn't seem like a big deal when we bought this house, but I would change it now in a heartbeat. No one wants to carry their laundry up and down 2 flights of stairs, not on a daily basis. It will become a chore, eventually.
When you are sick, when the family has the stomach flu, when you are doing everyone's laundry, when you are just tired... It will get harder and harder.
In my case, we moved in and I developed chronic health issues. Maybe my response is colored by that, but honestly, you can't know what's in the future.
FWIW, the people who built our house had the option of putting the W/D in the space that is my desk. :) They opted for the basement, and I lament this daily! I would so much prefer to have convenient laundry, and a different desk option.
All that said, I would understand if you opted for the desk and the picture window. :)