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PSA: mandarins, clementines and drug interactions


Laurie4b
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I followed up on something random I had read on the internet a couple weeks ago about tangerines and mandarins being different names for the same fruit. (Clementines as well.) The producers just put "Clementine" or "Madarin" on their products. I thought they were either oranges or a different citrus altogether.

 

I already knew that when grapefruit affected a medication that tangerines are usually not recommended either.   After some research and discussion with a pharmacist, I found that it is true: mandarins, clementines, and tangerines are all the same basic fruit and interact with the drug I'm on, blocking its effectiveness. I discussed this with the doctor today and she didn't know about it either. I'm frustrated because I'm a very compliant patient and would not have been eating them had I known. (For the drug I am on, moderate amounts are okay. I LOVE them and don't stick to moderate amounts. Never saw a need to!)

 

Anyway, I thought I'd share with others of you in case you're on a drug that interacts with grapefruit because that usually means tangerines as well.

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This NIH link (undated) says that tangerines and so forth will not have the same effect:

http://www.cc.nih.gov/ccc/patient_education/drug_nutrient/grapefruit1.pdf

 

This 2012 Prevention article says that other fruits "could be" a problem but does not cite specific research: 

http://www.prevention.com/health/healthy-living/grapefruit-juice-shouldnt-be-mixed-some-medications

 

Most of the links I looked at said that tangerines are not a problem. Tangelos can be, because they are a cross between tangerines and grapefruit. 

 

ETA one more link from the FDA that refers to tangelos and Seville oranges (used to make marmalade) as well as grapefruit: 

http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/UCM292839.pdf

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This NIH link (undated) says that tangerines and so forth will not have the same effect:

http://www.cc.nih.gov/ccc/patient_education/drug_nutrient/grapefruit1.pdf

 

This 2012 Prevention article says that other fruits "could be" a problem but does not cite specific research: 

http://www.prevention.com/health/healthy-living/grapefruit-juice-shouldnt-be-mixed-some-medications

 

Most of the links I looked at said that tangerines are not a problem. Tangelos can be, because they are a cross between tangerines and grapefruit. 

 

ETA one more link from the FDA that refers to tangelos and Seville oranges (used to make marmalade) as well as grapefruit: 

http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/UCM292839.pdf

 

A research medical article warns about tangerine consumption with the particular drug that I take. It's a moderate warning and people who consume them in moderation are okay. Trouble was that I consumed them immoderately! The pharmacist confirmed the information. I don't want to publish my meds online, so I can't link the article. It was from a medical publication, not a popular news site.

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I followed up on something random I had read on the internet a couple weeks ago about tangerines and mandarins being different names for the same fruit. (Clementines as well.) The producers just put "Clementine" or "Madarin" on their products. I thought they were either oranges or a different citrus altogether.

 

I already knew that when grapefruit affected a medication that tangerines are usually not recommended either.   After some research and discussion with a pharmacist, I found that it is true: mandarins, clementines, and tangerines are all the same basic fruit and interact with the drug I'm on, blocking its effectiveness. I discussed this with the doctor today and she didn't know about it either. I'm frustrated because I'm a very compliant patient and would not have been eating them had I known. (For the drug I am on, moderate amounts are okay. I LOVE them and don't stick to moderate amounts. Never saw a need to!)

 

Anyway, I thought I'd share with others of you in case you're on a drug that interacts with grapefruit because that usually means tangerines as well.

 

Good to know, I used to be on a med that restricted grapefruit. I didn't know about the others.

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Everyone, obviously check on your particular drug. I wouldn't want to deny anyone the pleasures of mandarins and clementines who doesn't need to be concerned! As Katilac linked upthread, some drugs are not affected by tangerines. Mine is. It's just something to check on. (I really wish that mandarin and clementine producers just labeled their products as tangerines at least somewhere on the bag.)

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Everyone, obviously check on your particular drug. I wouldn't want to deny anyone the pleasures of mandarins and clementines who doesn't need to be concerned! As Katilac linked upthread, some drugs are not affected by tangerines. Mine is. It's just something to check on. (I really wish that mandarin and clementine producers just labeled their products as tangerines at least somewhere on the bag.)

I'm glad you posted about it, because I don't think it's common knowledge that there was even the possibility of an issue. :)

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