Allison TX Posted May 15, 2012 Share Posted May 15, 2012 Have you had trouble stopping Zofran? I am 25 weeks pregnant and have been taking Zofran since about week 6. I was vomiting about 20 times a day, and could keep nothing down. The Zofran helped me feel a little better, but not great. I have only recently, within about the last month or so, started to feel better. I keep trying to quit the Zofran, I'm down to one pill a day, but I end up feeling yucky and throwing up after a day or two of not taking it. Is this a "rebound"? It seems the drug should be out of my system within a few hours, so why do I feel okay until about 36 hours off the meds? Anyone else have this problem?:confused: (my dr. does not understand why this is happening, and suggested a visit to the GI dr.) Quote Link to comment Share on other sites More sharing options...
wy_kid_wrangler04 Posted May 15, 2012 Share Posted May 15, 2012 Hmmm It sounds to me like you may have HG. I had that with my last 2 pregnancies. I was in and out of the hospital. I was on Zofran the whole time. Infact, with my youngest, I had a zofran pump through Matria. If you are still that nauseated I would stick with the Zofran. It lasted the whole pregnancy for me. Quote Link to comment Share on other sites More sharing options...
frugalmama Posted May 15, 2012 Share Posted May 15, 2012 I'd stick with the Zofran if it's working - while it didn't work for me with my HG it is great for those it works for. I had to stay on Compazine until I was well into the 3rd trimester with dd, and only then could I wean off it. Quote Link to comment Share on other sites More sharing options...
Mrs Mungo Posted May 15, 2012 Share Posted May 15, 2012 I have not, but one of my best friends did. Zofran was originally for cancer patients; her dad is an oncologist and said it was safe for baby. She eventually got down to a half pill, but she never fully got off of it until baby was born. Quote Link to comment Share on other sites More sharing options...
Jann in TX Posted May 15, 2012 Share Posted May 15, 2012 I took it when pg with youngest dd (now 10y). 'Back in those days' it was suggested that you only took it on occasion. While it is 'safe', taking it on a regular basis can create a habit of sorts. Lately more and more of my pg friends and family are prescribed this for REGULAR morning sickness... it used to be reserved for the few who were in danger of becoming dehydrated or unable to eat. Most of my friends also had a hard time coming off the drug after taking it regularly. ((hugs))... I know how bad it can be... my last pregnancy was TOUGH... Zofran gave me some sort of a life (and probably saved my baby too). Quote Link to comment Share on other sites More sharing options...
lisamarie Posted May 15, 2012 Share Posted May 15, 2012 I took it with #2 and was able to stop around week 20. With #3 I had to take it pretty much the entire pregnancy. But I had hyperemesis with all 3 pregnancies (I would have taken it with #1 had I known that throwing up all day wasn't normal). Quote Link to comment Share on other sites More sharing options...
HollyDay Posted May 15, 2012 Share Posted May 15, 2012 I took Zofran (and Reglan) with my youngest dd. Initially, we used the Reglan pump and oral Zofran and about 22-23 weeks I was able to come off everything. But, I had to go back on Zofran later in the pregnancy. As far as I know (for what that is worth), the nausea is coming from the pregnancy (yes, I had HG) not the rebound of the drug. Quote Link to comment Share on other sites More sharing options...
WeeBeaks Posted May 15, 2012 Share Posted May 15, 2012 Yes, I took it my last pregnancy thankfully. I had HG all my pregnancies, multiple hospital admissions. I had to take Zofran right up to the day of delivery, stopped it cold, no problems after delivery. For me, it was not the drug rebound effect at all. I just had vomiting if I didn't take it because of the pregnancy itself. That resolved with the delivery. ;) Quote Link to comment Share on other sites More sharing options...
Allison TX Posted May 15, 2012 Author Share Posted May 15, 2012 Thank you all. I had no idea so many people have had severe pregnancy sickness too. In real life, I know of no one else that has been as sick as I have been. This is my 4th pregnancy, and I've had morning sickness to some degree with all of them, this one has just been by far the worst. This is my second day off the Zofran, and I haven't thrown up (yet) this time. I'm just really nauseated. If I still feel like this tomorrow, or start throwing up again, I'll resume the Zofran, and assume I just need to be on it until baby comes. I just though by 25 weeks I shouldn't need it anymore! Thanks! Quote Link to comment Share on other sites More sharing options...
WiseOwlKnits Posted May 15, 2012 Share Posted May 15, 2012 I took Zofran with all 3 pregnancies. It didn't work for any of them though...nothing actually worked for any of them. All 3 times, it went away within an hour of them being born. If it works, I'd continue it until the baby comes! Quote Link to comment Share on other sites More sharing options...
Whereneverever Posted May 15, 2012 Share Posted May 15, 2012 I'm currently taking iv Zofran. My last pregnancy I was able to come off it in my third trimester, this one is much worse. If it helps, take it! Quote Link to comment Share on other sites More sharing options...
All4one Posted May 15, 2012 Share Posted May 15, 2012 My fourth pregnancy was the worst for nausea and vomiting. It lasted until 32 weeks. I took Zofran with my last 4, and I think it was diclectin (?) with my first. I couldn't function without it and my kids are perfect :) most of the time :tongue_smilie: Quote Link to comment Share on other sites More sharing options...
alisoncooks Posted June 4, 2012 Share Posted June 4, 2012 Another Zofran user here. :) With my 2nd, I was on it until about Wk 35. I started around Wk 6. Quote Link to comment Share on other sites More sharing options...
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