sbgrace Posted October 3, 2022 Share Posted October 3, 2022 I've been prescribed 7 days of doxycycline for a likely long-standing, asymptomatic infection. I do not think exactly when I start this antibotic matters a lot, within reason. A household member has chronic c-diff. So I generally try to avoid antibiotics as much as possible for everyone here, but I can't avoid this one. I will use Florastor while taking it. I have a colonoscopy scheduled 17 days from tomorrow. I have a call into the GI for his opinion on this, but I'm not sure he'll have one and his office already didn't return my call on Friday. WWYD: -Take antibiotic this week (with florastor) and then try to probiotic build my gut the week leading up the colonoscopy prep? -Postpone the antibiotic until after the colonoscopy? How long? -Do you think timing doesn't matter either way? Quote Link to comment Share on other sites More sharing options...
KSera Posted October 3, 2022 Share Posted October 3, 2022 I think timing matters, but I’m not sure which would be better. Depends how urgent the colonoscopy. I know they can be hard to schedule—any chance they’d move it back another two weeks so you would have a month to get your gut back in order after antibiotics. Definitely hit the florastor hard, not just one a day, but also I’m pretty sure doxycycline is one of the antibiotics less likely to cause c diff. If you didn’t live with someone colonized, I wouldn’t be so concerned about it with that antibiotic. Quote Link to comment Share on other sites More sharing options...
Jean in Newcastle Posted October 3, 2022 Share Posted October 3, 2022 The colonoscopy is looking for polyps or cancer. I don’t think that your gut biome will affect that. 4 Quote Link to comment Share on other sites More sharing options...
KSera Posted October 3, 2022 Share Posted October 3, 2022 (edited) 1 hour ago, Jean in Newcastle said: The colonoscopy is looking for polyps or cancer. I don’t think that your gut biome will affect that. Doing the complete clean out required before hand is a major disruption to the gut biome, so I think it’s a reasonable concern for someone consistently exposed to c diff. eta: Oh, I think I understand what you were saying now. I think you were looking at the concern from the opposite direction I am. I am reading it as she’s concerned about creating the conditions likely to be friendly to c diff, while you were thinking she was worried the antibiotic would affect the results of her colonoscopy. I don’t think the latter would be the case at all, but I think it’s not unreasonable for her to take precautions against the former. Edited October 3, 2022 by KSera 1 Quote Link to comment Share on other sites More sharing options...
Jean in Newcastle Posted October 3, 2022 Share Posted October 3, 2022 The gut biome is restored in 14 days after colonoscopy prep. https://www.nature.com/articles/s41598-019-40182-9 So it's a concern but not a catastrophic one. ) (BTW - I have had c-diff. I have also had a colonoscopy. I didn't find the colonoscopy prep to be that devastating. I did take probiotics afterwards. ) 2 Quote Link to comment Share on other sites More sharing options...
KSera Posted October 3, 2022 Share Posted October 3, 2022 2 hours ago, Jean in Newcastle said: The gut biome is restored in 14 days after colonoscopy prep. https://www.nature.com/articles/s41598-019-40182-9 Very helpful info, thanks! Quote Link to comment Share on other sites More sharing options...
Katy Posted October 3, 2022 Share Posted October 3, 2022 It doesn’t matter at all for a cancer check. Quote Link to comment Share on other sites More sharing options...
kbutton Posted October 3, 2022 Share Posted October 3, 2022 No advice on timing, but I would stay on the Florastor for more than one bottle and maybe taper. Quote Link to comment Share on other sites More sharing options...
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