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BeachGal

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  1. Most women might be getting just enough choline to keep their placenta healthy especially if their bodies are taking it from other elsewhere such as moving fat out of the mother's liver, which is another thing choline does. Choline deficiency is only one of a number of factors that are believed to cause pre-eclampsia. The article isn't saying it's the only factor, just an important one that has only been studied in the past two decades or so. The problem with choline is that it's not really known how much a person or even a population needs. Currently, it's based on adequate intake which is an educated guess. Pregnant women, however, do need more, and in the past few years, there's been a push for manufacturers of prenatal vitamins to increase the choline.
  2. Fewer than 10% of pregnant women are getting the adequate intake (AI, a guesstimate) of choline which plays a major role in preventing pre-eclampsia. https://www.seattletimes.com/life/wellness/choline-the-essential-but-forgotten-nutrient/ Some people also need more choline than others due to their genetics. Chris Masterjohn has some articles online that explains this and more in detail. https://chrismasterjohnphd.com/?sfid=1177&_sf_s=choline
  3. Yes. I mentioned that the antibodies are taken from the plasma of recovered patients in my original post. The CDC was taking samples from quarantined people here in the US in part for this reason. As for the limitations, that depends upon how long the process takes and if the antibodies can be grown in a lab. I know they first have to find the antibodies that match the virus. Then they have a number of other steps as well. I'm just curious how this will develop.
  4. Washable, reusable masks good for about 100 washes that might be available in the near future: They haven’t been tested for COVID19 but they do protect against some strains of flu viruses. Sonovia has enough material to make 5,000 to 10,000 face masks but need financial backing. https://www.israel21c.org/new-antiviral-masks-from-israel-may-help-stop-deadly-virus/
  5. What they’re doing is harvesting certain antibodies from plasma that’s been removed from people who’ve recovered. Those particular antibodies are then injected into patients who are very ill. It’s supposedly having a good effect but it’s not known how long a treatment will last. Probably a few days or so. That might be long enough for some, though. I don’t know anything about how long it would take to mass produce the antibodies. In the US a company called Regeneron is doing this. It’s also being done in Russia but I don’t know the company’s name. https://www.statnews.com/2020/02/05/in-the-race-to-develop-a-coronavirus-treatment-regeneron-thinks-it-has-the-inside-track/
  6. I don’t know but that would seem plausible. According to Dr. Cron, who is both an MD and researcher, it’s caused by mutations in the proteins that are involved with the perforin pathway. He estimates some 10-15% of the population have these mutations. So far, I’ve read LYST and PRF1 genes but haven’t yet found which snps. I’m going to keep looking. The real problem is that a cytokine storm will just look like a worse version of the initial infection when actually, the cytokine storm is a separate problem that needs its own treatment. Once that’s done, the original infection stands a better chance of healing up.. The CytoSorb device that can filter out cytokines is a game changer, though.
  7. VA portion of people getting extremely sick probably are experiencing a cytokine storm which is more common than previously thought. About 10-15% of humans are believed to have the genetic mutations in about 10 or so proteins involved with the perforin pathway. Perforin is something your body uses to punch holes in cancer cells or pathogens. Then, a toxic substance is poured in to kill the cell. With the genetic mutations, though, cytokines have to work much harder and that is what seems to cause the storm. The problem is that a patient is sick from the virus and sick from the cytokine storm. Basically, there are two separate problems occurring. Cytokine storm almost always will have fever and very high serum ferritin. Tamping down the cytokines with meds can be difficult but now there’s a blood-filtering device called CytoSorb which can filter out some of those excess cytokines. The company that makes it wants to use it in China. https://www.ptcommunity.com/wire/cytosorb-wuhan-coronavirus-and-cytokine-storm https://www.uab.edu/reporter/know-more/publications/item/8909-here-s-a-playbook-for-stopping-deadly-cytokine-storm-syndrome The Lancet recently mentioned that a portion of the very sickest have cytokine storm. If that can be determined early on, the proper treatment can be given helping people to survive. This virus is pretty nasty and is making its way over here. Best to be informed. ETA In people with the genetic mutations, cytokines will be multiplying as well, creating up to 5 times more.
  8. Are you running a fever at all? If yes, get your serum ferritin tested. If it’s high, you might actually have a cytokine storm as well as pneumonia. Fever and high ferritin are the two main symptoms. There is a super nifty device now that can filter cytokines out of blood, too, and a number of larger medical facilities have it now. It’s called the CytoSorb. If no fever, then my vote is to see a pulmonologist soon. Do you have a pulse oximeter?
  9. The Chief Actuary of Social Security and his staff run projections which determine in large part changes in retirement rules. Politicians also take the info (which they rarely understand) and use it as a means to try to get what they want. The process is pretty complex.
  10. Los Alamos National Lab came out with new numbers yesterday in a preprint that is yet to be peer reviewed. The authors are considered to be top notch, though. COVID19 is more infectious than we were being led to believe. In Wuhan, it’s R0 (R naught, rate of transmissibility) is 4.7 - 6.6. 6.6 is the upper limit and it’s likely a bit lower. However, it is 2-3 times more infectious than previously thought. Many variables are used to calculate R0. It can change from region to region, among different populations, etc. The virus also mutates and that can affect it as well. Likely, it will be better in some areas and worse in others. https://www.medrxiv.org/content/10.1101/2020.02.07.20021154v1
  11. I'm not sure who writes the script but it's handy for checking labs myself! I'm usually checking vitamin D, A1C1, sometimes an iron panel (my numbers can be weird) and occasionally a few oddball things out of curiosity. I mean, I can only do so much because labs cost money that I'd rather use for fun stuff! I use our HSA to pay.
  12. They are spraying down areas with a bleach solution and Decon 7, a hydrogen peroxide solution. That's good. It's a lot of work but will help to prevent transmission. China has ordered huge amounts of Decon 7 which is capable of killing the virus for 8 hours and is made here in the US by Decon7 Systems. They recently opened three more plants and are running double shifts to meet demand. Typically, it would be shipped but these are going by air. I wonder if more countries will be placing orders as well. Here is some information about two of the babies. https://www.reuters.com/article/us-china-health-disinfectants/u-s-disinfectant-maker-boosts-output-as-china-hospitals-battle-virus-idUSKBN1ZX0J9 The authorities say the girl, Jiang Moumou, who caught it at one month, is stable. That is good. https://www.newsweek.com/coronavirus-infects-1-month-old-baby-china-health-officials-say-1485525 The baby who tested positive at 30 hours has shortness of breath and is being treated. He looks full-term which is also good.
  13. That information is yours. You can be very pleasant about asking for a copy but don't feel in the least bit guilty asking for a copy of your lab results. I used to request mine (and my husband's and kids') at every appointment. Nowadays, the MDs we see post our results online so no need to ask them for a copy. You can get labwork done at places like WalkInLab if your state allows it (a few don't). You just go online, set up an account, find what you need, buy the test, print the necessary paperwork, make an appointment (not always necessary) and go in to a lab where they will do the test. Read or chat with someone at the website about prepping for the test -- fasting, avoiding certain foods, etc. Results are posted online. I do this for certain tests that I prefer to monitor myself. https://www.walkinlab.com They always have some sort of sale going on, so you might want to make an account first so you can get the discount (usually through email). I get one email per day from them about sales.
  14. Not yet but I'm hoping they're all improving. Hoping no news is at least "okay news."
  15. That number comes from what China wrote up in their paper. I don't know if other countries have written about this. I imagine the cruise ship will be analyzed. The transmission in Hong Kong, from what I've read, was caused by either a fan pulling the toilet spray into other apartments or faulty plumbing. The fan seems pretty likely. I have lived in buildings with over 700 apartment units and I can see how venting could move viruses from apartment to apartment. A nightmare. I have read that sometime this week in Virology, China is supposed to publish their results using ozone to kill CODIV in hospitals in. That will be interesting.
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