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No MMR-Autism Link in Large Study of Vaccinated vs. Unvaccinated Kids


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Wapiti,

You raise an important point.  While MRI's can provide a picture of the different brain regions.

These are just pictures of the 'end result'.

What is far more important, are the processes that are happening with the neurons and nerve cells.

Understanding the dynamics of the brain and how it is maintained and operated.

 

While many studies use MRI's to show the volumes of different brain regions.

What is more interesting, are the processes that can vary the volume?

 

Where the brain is the residence for a multitude of different species of Enzymes.

Each of these Enzymes have a dedicated role.

It is these Enzymes, that make use of our Genes.

So that each type of Enzyme, uses a specific Genetic Code within our Genes.

As their 'instruction manual'.

Which basically guides them in putting a certain molecule together.

Then what to do with it.

 

Where some Enzymes are involved with 'building and maintenance'.

While other Enzymes, are involved with operating our organs, or our muscles.

Then other Enzymes use parts of brain, to create thinking.

 

So that when we talk about brain and learning differences?

We are really talking about different ways that the Enzymes function.

 

Though these Enzymes, are vulnerable to certain different bacteria and viruses.

Which can attach themselves to certain Enzymes.

Causing them to dysfunction.

Over time, they can also cause irreversible changes to the genetic that the Enzyme uses.

But the bacteria/ virus, also causes 'physical changes' to the Enzyme.

 

Which often results in our 'immune system', recognising the changes, and wrongly identifying the useful Enzyme as a foreign invader.

That it will then attack and destroy.

Which means that this Enzyme is no longer, to carry out its functions.

 

So that while an MRI can show a picture of the different Departments in the brain, and the Corridors between.

They can't show the activity that is going on inside them?

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So that while an MRI can show a picture of the different Departments in the brain, and the Corridors between.

They can't show the activity that is going on inside them?

Only MRI technology does not stop at structural MRIs.

 

"Although fMRI uses the same principles as MRI, there is one important distinction. MRI (often called structural MRI) reveals brain anatomy, while fMRI reveals brain function, often in the form of neural activity. For this reason, fMRI is very useful for neuroscience and clinical research, while MRI is traditionally used for clinical characterization in the same manner as CT scans.

 

However, fMRI doesn’t reveal neural activity directly. Recall that when neurons are active, they fire action potentials and send messages in the form of neurotransmitters to other neurons. (To read more about this, click here.) While other imaging methods such as EEG (electroencephalography) can measure this activity directly, they often come with severe limitations such as poor spatial resolution. Instead, fMRI studies neural activity indirectly by measuring the BOLD (Blood Oxygenation Level Dependent) signal. This method is based on the fact that hemoglobin carrying a bound oxygen molecule (oxyhemoglobin) in the bloodstream emits a different MR signal than oxygen-depleted hemoglobin (deoxyhemoglobin). When parts of the brain become active, such as when a person is carrying out a cognitive task, they use up more oxygen than relatively inactive parts of the brain. You might think that this would result in a relative decrease in the level of oxygen in the active areas compared to the inactive areas, but actually the reverse happens! Because oxygen is being depleted, the brain compensates for the loss by increasing the flow of oxygenated blood to the active area. There is a slight overcompensation, which causes an increased oxyhemoglobin to deoxyhemoglobin ratio. As this ratio increases, the BOLD signal gets stronger. Essentially the BOLD signal measures the ratio of oxyhemoglobin to deoxyhemoglobin in the brain, which enables researches to indirectly gauge neural activity: higher neural activity = higher oxyhemoglobin to deoxyhemoglobin ratio = stronger BOLD signal."

 

Found here (this also explains how MRIs work):

http://web.stanford.edu/group/hopes/cgi-bin/hopes_test/neuroimaging/#functional-magnetic-resonance-imaging-fmri

 

More details on how fMRIs work can be found here:

http://science.howstuffworks.com/fmri.htm

 

I also noticed this, in the list of people for whom it would not be recommended (from the previous link, pg. 3)

 

"Although an fMRI test doesn't use radiation, its strong magnetic field and radio waves may not be recommended for certain groups of people including:

 

Pregnant women

People with an internal defibrillator or pacemaker

Those with artificial heart valves or limbs

People with cochlear implants

People with an infusion catheter

Those with clips used on brain aneurysms

Women with an intrauterine device (IUD)

People with metal pins, screws, plates or surgical staples."

 

Here's the direct link to page 3:

http://science.howstuffworks.com/fmri2.htm

 

Also, MRIs are to be excluded by the same list of people:

 

"In most cases, an MRI exam is safe for patients with metal implants, except for a few types. People with the following implants cannot be scanned and should not enter the MRI scanning area:

 

cochlear (ear) implant

some types of clips used for brain aneurysms

some types of metal coils placed within blood vessels

nearly all cardiac defibrillators and pacemakers"

 

Found here:

https://www.radiologyinfo.org/en/info.cfm?pg=headmr

 

This means that your little girl, Crimson Wife, would be excluded due to her implants. So there may have been a number of reasons why you were told what you were. Someone would have to hear the comment in context.

 

I am not trying to put anyone on the spot here. Just researching and then researching some more based on comments made here, and then sharing my findings. I'm only seeking out the facts, as supported by credible sources, and that is what I am sharing. For anyone interested that is! This whole thread has been about looking at how far the research on autism has come!

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Here's the 2011 study mentioned in the previous link:

 

Balance tips toward environment as heritability ebbs in autism?

https://www.nih.gov/news-events/news-releases/balance-tips-toward-environment-heritability-ebbs-autism

 

OK, and now I'll walk away LOL. I do tend to get obsessive when it comes to research!

This is interesting. I have 7 year old identical twin daughters. One is on the spectrum (formally diagnosed two years ago) and the other is not. Both have been vaccinated.

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