Jump to content

Menu

wuhan - coronavirus


gardenmom5

Recommended Posts

On 8/24/2021 at 6:31 PM, Not_a_Number said:

I think given Delta, masking is kind of like using a tissue for birth control instead of a condom... I mean, it's POSSIBLE it'll make a difference, but it's going to be wildly inadequate given the viral load likely to be occurring within the schools. 

I'm totally, totally not comfortable with being indoors with people right now because Delta is so contagious, but I did read something today that summarized several recent studies that did make me feel better about my (vaccinated) college kids returning to their fully masked, vaccine mandated schools. It showed a dramatic difference with universal masking even with Delta. One recently published in Nature found a 75% reduction in infections with 80% of people wearing masks. That's way better that what I would expect from a tissue used in place of a condom   This is the full substack article that summarizes some of the data:

https://emilysmith.substack.com/schools-and-churches-heres-the-data

 

 
23 hours ago, lewelma said:

I think given Delta, masking is kind of like using a tissue for birth control instead of a condom... I mean, it's POSSIBLE it'll make a difference, but it's going to be wildly inadequate given the viral load likely to be occurring within the schools. 

 

Super impressive.

  • Like 9
Link to comment
Share on other sites

25 minutes ago, Melissa Louise said:

People here are apparently dying at home 'under the care of' the local health service. Are they just deteriorating incredibly rapidly? Not presenting to hospital? Or being discouraged from taking up a bed? People in their 30's. Scary. 

I wonder if they are monitoring oxygen levels like many in the US seem to be?

Link to comment
Share on other sites

On 8/24/2021 at 3:45 PM, Melissa in Australia said:

Or perhaps more of the population in Australia is interested in working together  and trying to eliminate this thing.

We moved around much more than Australians here back in Dec-Mid March 2020 so it was already so widespread in the US but our testing was almost non-existent then.  There was absolutely no way that in our country-which has a population of more than 10x Australia's and that has a gigantic immigrant problem (in July, we had over 225,000 people enter through border crossings without permission and who knows how many crossed with no accounting in our giant land borders, not counting all the people who come on VISA waivers and just stay or on VISAs and just stay.)  

 

  • Like 1
Link to comment
Share on other sites

5 hours ago, Ausmumof3 said:

What do we think about speculation that Astra Zeneca may give longer lasting immunity than the MRNA vaccines?  Would you be more likely to risk the blood clot issue of it meant not needing six monthly or sooner booster shots? How much longer would immunity have to last to make it worthwhile?

NOt me.  I do get blood clots already.

Link to comment
Share on other sites

1 hour ago, TravelingChris said:

We moved around much more than Australians here back in Dec-Mid March 2020 so it was already so widespread in the US but our testing was almost non-existent then.  There was absolutely no way that in our country-which has a population of more than 10x Australia's and that has a gigantic immigrant problem (in July, we had over 225,000 people enter through border crossings without permission and who knows how many crossed with no accounting in our giant land borders, not counting all the people who come on VISA waivers and just stay or on VISAs and just stay.)  

 

Plus we don't have to pay for tests.

Link to comment
Share on other sites

1 hour ago, TravelingChris said:

NOt me.  I do get blood clots already.

yes that’s totally understandable.  I felt pretty terrible after the second Pfizer so having it every six months is bothering me a lot. If we can even get supplies for that.  So I’m hopeful that some of the later generation or different style vaccines are longer lasting or more broad  than MRNA.  Don’t get me wrong I’m extremely grateful to have had access to Pfizer when I did and wouldn’t make a different decision but definitely would prefer not to have to have six monthly boosters.

Edited by Ausmumof3
  • Like 1
Link to comment
Share on other sites

6 hours ago, KSera said:

I'm totally, totally not comfortable with being indoors with people right now because Delta is so contagious, but I did read something today that summarized several recent studies that did make me feel better about my (vaccinated) college kids returning to their fully masked, vaccine mandated schools. It showed a dramatic difference with universal masking even with Delta. One recently published in Nature found a 75% reduction in infections with 80% of people wearing masks. That's way better that what I would expect from a tissue used in place of a condom   This is the full substack article that summarizes some of the data:

https://emilysmith.substack.com/schools-and-churches-heres-the-data

This is not using a real study, though. This is a model: 

https://www.nature.com/articles/s41598-021-94960-5?fbclid=IwAR0WqAUL0KpjH9hJy2Wb1uKWC6p6idkDXk_8HrDXot3q8iJseYI2ORVOADk

I'll believe it when I see someone ACTUALLY compare what happens with a mask and without. I am sure I was exaggerating there (I feel quite frustrated!), but having seen how people wear masks, it would really surprise me if masks in school would make enough of a difference. People have to take masks off to eat. People's masks slide down past their noses. People are indoors the whole day. 

Basically, I imagine that masks will mean that it takes a few weeks longer for everyone to get Delta, not that we manage to keep transmissions controllable. I hope I'm wrong, I do. But that's my current sense. 

  • Like 3
Link to comment
Share on other sites

10 minutes ago, Not_a_Number said:

This is not using a real study, though. This is a model: 

https://www.nature.com/articles/s41598-021-94960-5?fbclid=IwAR0WqAUL0KpjH9hJy2Wb1uKWC6p6idkDXk_8HrDXot3q8iJseYI2ORVOADk

I'll believe it when I see someone ACTUALLY compare what happens with a mask and without. I am sure I was exaggerating there (I feel quite frustrated!), but having seen how people wear masks, it would really surprise me if masks in school would make enough of a difference. People have to take masks off to eat. People's masks slide down past their noses. People are indoors the whole day. 

Basically, I imagine that masks will mean that it takes a few weeks longer for everyone to get Delta, not that we manage to keep transmissions controllable. I hope I'm wrong, I do. But that's my current sense. 

I agree.  I have to be honest my mask feels kind of ineffective when I’m in a small room for several hours with people.  For half an hour or an hour it might be ok but feels like the concentration of germs after 4-5 hours is too high for it to really work.  Don’t get me wrong I still think it’s worth it for the occasional contract risks just not where a pool of people are together all day.

  • Like 1
Link to comment
Share on other sites

6 minutes ago, Ausmumof3 said:

I agree.  I have to be honest my mask feels kind of ineffective when I’m in a small room for several hours with people.  For half an hour or an hour it might be ok but feels like the concentration of germs after 4-5 hours is too high for it to really work.  Don’t get me wrong I still think it’s worth it for the occasional contract risks just not where a pool of people are together all day.

Exactly. I mean, if everyone had their mask taped their face and no one ever ate or drank and everyone was super rigorous, then maybe it’d be enough. But we’re talking real-life use with a variant with extremely high viral loads.

We’re currently masking in crowds outdoors. I figure the masks will help if there’s a stray cloud of virus or something. I just don’t trust them in a room where the particles have been building up.

Edited by Not_a_Number
  • Like 1
Link to comment
Share on other sites

20 minutes ago, Not_a_Number said:

Exactly. I mean, if everyone had their mask taped their face and no one ever ate or drank and everyone was super rigorous, then maybe it’d be enough. But we’re talking real-life use with a variant with extremely high viral loads.

We’re currently masking in crowds outdoors. I figure the masks will help if there’s a stray cloud of virus or something. I just don’t trust them in a room where the particles have been building up.

How about in a room with air purifiers running full speed?

I feel like we knew masks helped with the previous variants.  It seemed clear they made a difference in places with mandates versus those without.  I think we still just don't know with Delta.  They may still help quite a bit.

  • Like 1
Link to comment
Share on other sites

46 minutes ago, Ausmumof3 said:

I agree.  I have to be honest my mask feels kind of ineffective when I’m in a small room for several hours with people.  For half an hour or an hour it might be ok but feels like the concentration of germs after 4-5 hours is too high for it to really work.  Don’t get me wrong I still think it’s worth it for the occasional contract risks just not where a pool of people are together all day.

But again, that's not what the mask is supposed to do - to protect you. The main point is it is supposed to keep your respiratory droplets from infecting others. That's why it has to be universal masking, not just individuals. 

  • Like 3
Link to comment
Share on other sites

2 hours ago, Rosie_0801 said:

Plus we don't have to pay for tests.

We don't either in many cases.  However, our problem w tests was that the first tests the CDC got in Jan-Mid March 2020 were badly manufactured and totally unreliable.  And the few reliable tests were being used on the coasts as if people travelling from China, UK, Italy, etc only ever go to certain cities on the coasts.  Yes, areas like NYC and Seattle area got it bad then but lots of places had lots of deaths and cases by mid March and the spread continued.  And then came Delta.

Link to comment
Share on other sites

2 hours ago, Ausmumof3 said:

https://www.washingtonpost.com/nation/2021/08/26/covid-delta-variant-live-updates/
 

US hospitalisation reach 100,000 for the first time since Jan 

Not just Covid now.  Dd2 had to go to ER on Wednesday night because her breathing was getting very bad.  Had a third or fourth Covid test, xrays were completely clear, and they did bloid tests too. Let her govw wrong prescription for prednisone, because at 3am and being sick, she didn't realize that she had been on Medrol where z 4 mg pill is equivalent to a 7.5 Prednisone dose 

Her fiancee is driving her up here today to see her allergist/immunologist who takes care of her asthma.  She needs her to certify sickness to her work so she gets short term disability and to give her a longer, slower steroid step-down. I don't know if they tested her for RSV or flu.

But people are showing up w other viruses now too and some are hospitalized.  Plus we have on many US cities z gigantic increase in violent crimes that cause victims to need treatment too.

  • Sad 5
Link to comment
Share on other sites

1 hour ago, ktgrok said:

But again, that's not what the mask is supposed to do - to protect you. The main point is it is supposed to keep your respiratory droplets from infecting others. That's why it has to be universal masking, not just individuals. 

Don’t get me wrong I don’t think their completely pointless.  They are going to protect against droplets and they’ll slow things down.  But where masks leak around the sides and top etc a few aerosols are escaping and over a full school day concentration can build up and particularly with higher viral load with delta that will likely happen faster. Masks are still going to help in situations where people are there for a short period of time. 

  • Like 2
Link to comment
Share on other sites

1 minute ago, TravelingChris said:

Not just Covid now.  Dd2 had to go to ER on Wednesday night because her breathing was getting very bad.  Had a third or fourth Covid test, xrays were completely clear, and they did bloid tests too. Let her govw wrong prescription for prednisone, because at 3am and being sick, she didn't realize that she had been on Medrol where z 4 mg pill is equivalent to a 7.5 Prednisone dose 

Her fiancee is driving her up here today to see her allergist/immunologist who takes care of her asthma.  She needs her to certify sickness to her work so she gets short term disability and to give her a longer, slower steroid step-down. I don't know if they tested her for RSV or flu.

But people are showing up w other viruses now too and some are hospitalized.  Plus we have on many US cities z gigantic increase in violent crimes that cause victims to need treatment too.

RSV is high this year.  That’s disappointing about the crime.  Our hospitals have a ramping issue here even without COVID - it’s going to be an absolute debacle when Covid gets going. 

  • Like 1
Link to comment
Share on other sites

32 minutes ago, TravelingChris said:

Not just Covid now.  Dd2 had to go to ER on Wednesday night because her breathing was getting very bad.  Had a third or fourth Covid test, xrays were completely clear, and they did bloid tests too. Let her govw wrong prescription for prednisone, because at 3am and being sick, she didn't realize that she had been on Medrol where z 4 mg pill is equivalent to a 7.5 Prednisone dose 

Her fiancee is driving her up here today to see her allergist/immunologist who takes care of her asthma.  She needs her to certify sickness to her work so she gets short term disability and to give her a longer, slower steroid step-down. I don't know if they tested her for RSV or flu.

But people are showing up w other viruses now too and some are hospitalized.  Plus we have on many US cities z gigantic increase in violent crimes that cause victims to need treatment too.

This stat is just for COVID, though.

  • Like 1
Link to comment
Share on other sites

2 hours ago, Wheres Toto said:

How about in a room with air purifiers running full speed?

I feel like we knew masks helped with the previous variants.  It seemed clear they made a difference in places with mandates versus those without.  I think we still just don't know with Delta.  They may still help quite a bit.

I have no idea. I’m sure it’s better than nothing. I’d guess that it’s not good enough. But what do I know?

Link to comment
Share on other sites

1 hour ago, TravelingChris said:

Not just Covid now.  Dd2 had to go to ER on Wednesday night because her breathing was getting very bad.  Had a third or fourth Covid test, xrays were completely clear, and they did bloid tests too. Let her govw wrong prescription for prednisone, because at 3am and being sick, she didn't realize that she had been on Medrol where z 4 mg pill is equivalent to a 7.5 Prednisone dose 

Her fiancee is driving her up here today to see her allergist/immunologist who takes care of her asthma.  She needs her to certify sickness to her work so she gets short term disability and to give her a longer, slower steroid step-down. I don't know if they tested her for RSV or flu.

But people are showing up w other viruses now too and some are hospitalized.  Plus we have on many US cities z gigantic increase in violent crimes that cause victims to need treatment too.

It's 100K just with covid, not counting other causes:

"More than 100,000 people are hospitalized with covid-19 in the United States, a level not seen since Jan. 30 — when coronavirus vaccines were not widely available — as the country grapples with the delta variant’s spread.

Hospitalizations are highest across the South, where every state in the region has a higher portion of its population currently hospitalized with covid-19 than the national level, according to a Washington Post database. More than 17,000 people are hospitalized with covid-19 in Florida, which has the most hospitalizations for covid-19 of any state in the country, followed by Texas, which has more than 14,000."

  • Like 2
  • Sad 3
Link to comment
Share on other sites

1 hour ago, Ausmumof3 said:

Don’t get me wrong I don’t think their completely pointless.  They are going to protect against droplets and they’ll slow things down.  But where masks leak around the sides and top etc a few aerosols are escaping and over a full school day concentration can build up and particularly with higher viral load with delta that will likely happen faster. Masks are still going to help in situations where people are there for a short period of time. 

Oh, totally agree. But where people have to be in a room together, it's better than nothing. 

  • Like 2
Link to comment
Share on other sites

7 hours ago, Melissa Louise said:

People here are apparently dying at home 'under the care of' the local health service. Are they just deteriorating incredibly rapidly? Not presenting to hospital? Or being discouraged from taking up a bed? People in their 30's. Scary. 

I saw that, but couldn’t find any details. Very concerning. 

4 hours ago, Not_a_Number said:

This is not using a real study, though. This is a model: 

https://www.nature.com/articles/s41598-021-94960-5?fbclid=IwAR0WqAUL0KpjH9hJy2Wb1uKWC6p6idkDXk_8HrDXot3q8iJseYI2ORVOADk

I'll believe it when I see someone ACTUALLY compare what happens with a mask and without. I am sure I was exaggerating there (I feel quite frustrated!), but having seen how people wear masks, it would really surprise me if masks in school would make enough of a difference. People have to take masks off to eat. People's masks slide down past their noses. People are indoors the whole day. 

Basically, I imagine that masks will mean that it takes a few weeks longer for everyone to get Delta, not that we manage to keep transmissions controllable. I hope I'm wrong, I do. But that's my current sense. 

I know that’s modeling. It’s hard to get a randomized study now because the evidence is strong enough that having a group not mask is unethical right now. There are a lot of real world analyses showing that places where universal masking in place are doing much better, but there will always be the argument of potential confounders, which I don’t think can be helped right now.

To me, the risk to people taking off their masks to eat in a room together isn’t an indictment of masks not working, it’s precisely showing that removing the masks is risky. I’d also like to see a continued encouragement to people to get and wear the best masks they can. I still can’t get over seeing people at this point in the pandemic with masks that keep falling down and needing to be pulled up that could clearly be fixed by shortening ear loops. Isn’t it just uncomfortable to have to keep fixing a mask like that? Shorten your ear loops! We need a PSA announcement about that. In my area though, I don’t see that much of that anymore. People are wearing better and better masks as time goes by. 

3 hours ago, Wheres Toto said:

How about in a room with air purifiers running full speed?

It seems to be about getting enough complete room air changes to keep virus from building up. If the air purifiers are sufficient, it seems very helpful. I’ve been reading both the recommendations from aerosol scientists and then comparing with what the schools my various loved ones will be attending are doing. Fortunately, all of them have had a detailed plan available for how they are addressing ventilation and air cleaning. I feel much better about kids going into an environment with everyone masked and 100% outdoor air coming through the HVAC to attain 6-8 complete air changes every hour. It might not be enough is someone is sitting right next to an infected kid their masks loosely worn, but I think it would do pretty well for people farther away, and for my own kids with their snug KF94s. They won’t be removing them inside to eat or drink. 

  • Like 4
Link to comment
Share on other sites

On a lighter note:

Dad strips at heated Texas school board meeting to make point on COVID mask mandate

The Dripping Springs Independent School District has a policy stating face masks are optional for the upcoming school year, according to the San Marcos Daily Record. At the beginning of an hours-long meeting on Monday, residents argued for and against adjusting that policy by enforcing stricter COVID-19 safety measures in classrooms.

When James Akers first approached the microphone for his allotted 90 seconds to speak before the board and the socially-distanced audience gathered in the auditorium, he was fully clothed. But that changed quickly.

“I do not like the government, or any other entity, telling me what to do,” Akers said while dressed in a jacket, pants, suit and tie. “But sometimes I’ve got to push the envelope a little bit. And I’ve decided I’m not just going to talk about it, I’m going to walk the walk.”

“At work they make me wear this jacket,” he said, pulling it off. “I hate it.”

“They make me wear this shirt and tie,” Akers continued. “I hate it.”

As he shed his clothes, Akers claimed he ran three stop signs and four red lights on the way to the meeting, adding “I have every right to drive as fast as I want to.” Upon arriving, he parked in a handicap space, Akers said while taking off his undershirt and dropping his pants to the ground, earning cheers and jeers from the audience.

Two police officers moved near the microphone, apparently ready to escort Akers out if he dared to remove his last article of clothing — which many Dripping Springs residents say was a bathing suit.

The whole display was to prove a point, he said: red lights, like masks, may be inconvenient, but they also save lives. “It’s simple protocol, people. We follow certain rules. We follow certain rules for a very good reason,” Akers said.

Board president Barbara Stroud grabbed her gavel, hammering the boos and applause into silence, bringing the meeting back to order.“Mr. Akers I understand — I believe you’re a swimmer — but if you wouldn’t mind putting your pants back on for a comment, that would be appreciated,” Stroud said.

https://www.star-telegram.com/news/nation-world/national/article253734628.html?fbclid=IwAR3cxyub8nomnqzlqaRkk8KIxyyoPQni7RYzx2kbVSsAeh-HnZQTW0hFMTs

  • Like 3
  • Haha 19
Link to comment
Share on other sites

8 hours ago, Melissa Louise said:

People here are apparently dying at home 'under the care of' the local health service. Are they just deteriorating incredibly rapidly? Not presenting to hospital? Or being discouraged from taking up a bed? People in their 30's. Scary. 

This was happening in the US in the early days. People didn’t realize how it could sneak up on them. Perhaps they still don’t in some areas. 

  • Like 3
Link to comment
Share on other sites

4 hours ago, Corraleno said:

On a lighter note:

Dad strips at heated Texas school board meeting to make point on COVID mask mandate

The Dripping Springs Independent School District has a policy stating face masks are optional for the upcoming school year, according to the San Marcos Daily Record. At the beginning of an hours-long meeting on Monday, residents argued for and against adjusting that policy by enforcing stricter COVID-19 safety measures in classrooms.

When James Akers first approached the microphone for his allotted 90 seconds to speak before the board and the socially-distanced audience gathered in the auditorium, he was fully clothed. But that changed quickly.

“I do not like the government, or any other entity, telling me what to do,” Akers said while dressed in a jacket, pants, suit and tie. “But sometimes I’ve got to push the envelope a little bit. And I’ve decided I’m not just going to talk about it, I’m going to walk the walk.”

“At work they make me wear this jacket,” he said, pulling it off. “I hate it.”

“They make me wear this shirt and tie,” Akers continued. “I hate it.”

As he shed his clothes, Akers claimed he ran three stop signs and four red lights on the way to the meeting, adding “I have every right to drive as fast as I want to.” Upon arriving, he parked in a handicap space, Akers said while taking off his undershirt and dropping his pants to the ground, earning cheers and jeers from the audience.

Two police officers moved near the microphone, apparently ready to escort Akers out if he dared to remove his last article of clothing — which many Dripping Springs residents say was a bathing suit.

The whole display was to prove a point, he said: red lights, like masks, may be inconvenient, but they also save lives. “It’s simple protocol, people. We follow certain rules. We follow certain rules for a very good reason,” Akers said.

Board president Barbara Stroud grabbed her gavel, hammering the boos and applause into silence, bringing the meeting back to order.“Mr. Akers I understand — I believe you’re a swimmer — but if you wouldn’t mind putting your pants back on for a comment, that would be appreciated,” Stroud said.

https://www.star-telegram.com/news/nation-world/national/article253734628.html?fbclid=IwAR3cxyub8nomnqzlqaRkk8KIxyyoPQni7RYzx2kbVSsAeh-HnZQTW0hFMTs

Oh boy, that's not all that far from me. 

This place is so exhausting. 

Link to comment
Share on other sites

4 hours ago, Jean in Newcastle said:

This was happening in the US in the early days. People didn’t realize how it could sneak up on them. Perhaps they still don’t in some areas. 

My cousin's spouse insisted he felt fine despite the pulse ox reading 81%. He ended up hospitalized for about a week, only because she argued with him about it and wouldn't let up.

When you don't have enough oxygen going to your brain, you can't figure out that you need help. 

  • Like 6
Link to comment
Share on other sites

22 minutes ago, Rosie_0801 said:

I beg your pardon. I thought people had mentioned having to pay earlier in this thread.

Tests at the county or state run sites are free. Tests at a pharmacy are free, but it can take days to get an appointment - was 4 days last I checked. An urgent care or doctors office can do them, and the test may be free, but the appointment may not be - at a regular doctor's office you will pay an exam fee. Over the counter tests are about 20 bucks for a 2 pack. 

  • Like 4
  • Thanks 2
Link to comment
Share on other sites

10 hours ago, Ausmumof3 said:

I agree.  I have to be honest my mask feels kind of ineffective when I’m in a small room for several hours with people.  For half an hour or an hour it might be ok but feels like the concentration of germs after 4-5 hours is too high for it to really work.  Don’t get me wrong I still think it’s worth it for the occasional contract risks just not where a pool of people are together all day.

 

10 hours ago, Not_a_Number said:

Exactly. I mean, if everyone had their mask taped their face and no one ever ate or drank and everyone was super rigorous, then maybe it’d be enough. But we’re talking real-life use with a variant with extremely high viral loads.

We’re currently masking in crowds outdoors. I figure the masks will help if there’s a stray cloud of virus or something. I just don’t trust them in a room where the particles have been building up.

Except that they really do seem to work in healthcare here - call it the Health Care Anomaly?  We're now 18 months into this with pleated earlobe masks for HCW in an overcrowded ED (packed WR, hallway chairs everywhere, wandering patients, people EVERYWHERE) with a good portion of patients not masked (dementia, physical or intellectual disability, respiratory emergency, altered level of consciousness, intoxication, {ETA or just non-compliant}) or improperly masked.  And we haven't had a single outbreak in my department - despite a steady stream of covid positive patients coming through.

HCW are better than most at wearing them properly, but really not as good as you'd think.  There is plenty of sneaking them off for a drink and snacks at the desk on nights.

We probably have better ventilation than most other public buildings, but not that much better than most newish construction, I don't think.  Odours definitely linger LOL.

ETA ; the ventilation in our positive pressure iso rooms is great when we flip them to PP mode.  We only have 3 of those though, so not representative....  The Covid + patients end up anywhere we can find a spot for them, including hallway chairs.  (we often don't know they were covid + until tests come back the next day)

Edited by wathe
  • Like 8
Link to comment
Share on other sites

1 hour ago, Melissa Louise said:

Do you think it's OTT if I bought an oximeter? 

Joining the chorus of buy one. I bought one early March 2020 as well, and had my parents do the same, and ours has come in handy. The price went up a good deal by April, but when I looked recently, was back down to where I could find a decent one well under $20 USD.

  • Like 4
Link to comment
Share on other sites

1 hour ago, Melissa Louise said:

Do you think it's OTT if I bought an oximeter? 

Not at all. Buy one. I’ve bought one for each set of grandparents, sent one to college with my dd and have one here at home. In this situation it’s something that would be good for all of us to have in our first aid kit.

  • Like 2
Link to comment
Share on other sites

49 minutes ago, wathe said:

 

Except that they really do seem to work in healthcare here - call it the Health Care Anomaly?  We're now 18 months into this with pleated earlobe masks for HCW in an overcrowded ED (packed WR, hallway chairs everywhere, wandering patients, people EVERYWHERE) with a good portion of patients not masked (dementia, physical or intellectual disability, respiratory emergency, altered level of consciousness, intoxication, {ETA or just non-compliant}) or improperly masked.  And we haven't had a single outbreak in my department - despite a steady stream of covid positive patients coming through.

HCW are better than most at wearing them properly, but really not as good as you'd think.  There is plenty of sneaking them off for a drink and snacks at the desk on nights.

We probably have better ventilation than most other public buildings, but not that much better than most newish construction, I don't think.  Odours definitely linger LOL.

ETA ; the ventilation in our positive pressure iso rooms is great when we flip them to PP mode.  We only have 3 of those though, so not representative....  The Covid + patients end up anywhere we can find a spot for them, including hallway chairs.  (we often don't know they were covid + until tests come back the next day)

That is encouraging!  Are you using proper N95s though or cloth/standard surgical masks?

One model I read implied about 8x reduction with masking and 16x with an open window.  It’s the sealed up stuffiness of the school environments here thats bothering me.

On a separate non Covid note I’ve come across a lot of info on sick building syndrome with modern buildings designed for energy efficiency with air conditioning and heating etc and not having adequate ventilation and it’s playing on my mind a lot.  I do think there was more wisdom than we give credit for in the late 19th century obsession with air quality.

  • Like 4
Link to comment
Share on other sites

14 minutes ago, Ausmumof3 said:

That is encouraging!  Are you using proper N95s though or cloth/standard surgical masks?

One model I read implied about 8x reduction with masking and 16x with an open window.  It’s the sealed up stuffiness of the school environments here thats bothering me.

On a separate non Covid note I’ve come across a lot of info on sick building syndrome with modern buildings designed for energy efficiency with air conditioning and heating etc and not having adequate ventilation and it’s playing on my mind a lot.  I do think there was more wisdom than we give credit for in the late 19th century obsession with air quality.

Pleated disposable earloop procedure masks.  A level below true surgical masks.  Definitely not fancy!

N95 reserved for AGMP's (aerosol generating medical procedures) only.

IMG_6367.jpeg

Edited by wathe
  • Like 5
Link to comment
Share on other sites

Bringing this over from the thread on 3rd doses. Preprint on a new variant from South Africa that is related to the Peruvian variant (Lambda / C.37). Two interesting take-aways: (1) it has mutations associated with both improved ACE2 binding and antibody escape and (2) they suggest that the much-higher-than-normal level of mutations in this variant might be the result of "prolonged viral infection" in a single individual.

"We have identified a new SARS-CoV-2 variant assigned to the PANGO lineage C.1.2. This variant has been detected throughout the third wave of infections in South Africa from May 2021 onwards and has been detected in seven other countries within Europe, Asia, Africa and Oceania. The identification of novel SARS-CoV-2 variants is commonly associated with new waves of infection. Like several other VOCs, C.1.2 has accumulated a number of substitutions beyond what would be expected from the background SARS-CoV-2 evolutionary rate. This suggests the likelihood that these mutations arose during a period of accelerated evolution in a single individual with prolonged viral infection through virus-host co-evolution1921. Deletions within the NTD (like Y144del, seen in C.1.2 and other VOCs) have been evident in cases of prolonged infection, further supporting this hypothesis2224.

C.1.2 contains many mutations that have been identified in all four VOCs (Alpha, Beta, Delta and Gamma) and three VOIs (Kappa, Eta and Lambda) as well as additional mutations within the NTD (C136F), RBD (Y449H), and adjacent to the furin cleavage site (N679K). Many of the shared mutations have been associated with improved ACE2 binding (N501Y)2529 or furin cleavage (H655Y and P681H/R)3032, and reduced neutralization activity (particularly Y144del, 242-244del, and E484K)17,3339, providing sufficient cause for concern of continued transmission of this variant. Future work aims to determine the functional impact of these mutations, which likely include neutralizing antibody escape, and to investigate whether their combination confers a replicative fitness advantage over the Delta variant.

The C.1.2 lineage is continuing to grow. At the time of submission (20 August 2021) there were 80 C.1.2 sequences in GISAID with it now having been detected in Botswana and in the Northern Cape of South Africa."

Source: https://www.medrxiv.org/content/10.1101/2021.08.20.21262342v2.full.pdf+html

Edited by Corraleno
  • Sad 6
Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

×
×
  • Create New...