So, I have been eating low carb and exercising regularly for three years now. I lost 35 lbs. in the first 6 months and kept it off, but then hit a stall at ten pounds above my goal weight...very close to it, though, so I was pretty content. But in two years, not another pound has come off, and in fact, I've gained back about 10-15 lbs. And I have NOT changed my eating or exercise habits other than decreasing my carb count and increasing my exercise (did not work) and then I tried eating a few more good carbs and decreasing my exercise (in case I was depriving my body, therefore causing it to hold on to weight.) Well, now I realize that since I started taking 30mg of Amitriptyline daily for migraine prevention, that is the time frame in which I gained this weight back and I CAN'T get it off. It was dropping like crazy prior to this time. How does medication itself make you gain weight? Water retention? Slowing effect on metabolism? Help!!!