School is usually done around the dining room table. I have most of their day-to-day stuff in a set of drawers there. A bookcase with their books is in the hallway, and a filebox for me is hiding in the dining room. I don't think I'd be able to keep all the school stuff in one room, so why try? I know they would not want to stay in one room.
We have a nice kitchen counter that dd9 works at when I need to help her. If she doesn't need me then she sits at the table, on the couch, on the floor, out on the deck, wherever is most comfortable for her.
Ds17 likes to roam. The only place he's not allowed is in his room - he tends to get distracted by his phone, the game system, or his guitar.
Works for us.