Definitely! We used to have weekly dinner/game nights with a few other couples, but haven't seen them in several years. First there were the shutdowns, then when that ended, one of the families demanded that everyone wear masks during the entire event (down to the ridiculous pull it down to take a bite of food, pull it back up to chew), and we weren't going to do that. I think they may have eased up some based on photos I've seen of them posted on their social media where they're out and about finally acting normal (they'd had their toddler in masks and surgical gloves before), but they haven't bothered to contact us since then, and we haven't bothered either.
There was another group of people we'd have frequent playdates with who all had kids who were within a month of our kid's age, and we haven't seen them all together since then---we've randomly run into one or two at the zoo or the grocery store, but nothing planned. They'd all just shut themselves in their homes for months and then once their kids got older, started sending them off to preschools and public school, and so we just drifted apart.
We have made new friends since everything happened though, so it's fine.